101382-56-3Relevant articles and documents
Design of new quinolin-2-one-pyrimidine hybrids as sphingosine kinases inhibitors
Abonia, Rodrigo,Andújar, Sebastián,Cobo, Justo,Enriz, Ricardo D.,Gutiérrez, Lucas,Insuasty, Daniel,Lima, Santiago,Marchal, Antonio,Nogueras, Manuel,Spiegel, Sarah,Vettorazzi, Marcela
, (2019)
Sphingosine-1-phosphate is now emerging as an important player in cancer, inflammation, autoimmune, neurological and cardiovascular disorders. Abundance evidence in animal and humans cancer models has shown that SphK1 is linked to cancer. Thus, there is a