101414-36-2Relevant academic research and scientific papers
REACTIONS OF THIIRANES. X. REGIOSELECTIVITY OF RING-OPENING IN METHYL- AND VINYLTHIIRANES BY PHENOLS
Tverdokhlebov, V. P.,Polyakova, N. Yu.,Tselinskii, I. V.
, p. 1258 - 1261 (2007/10/02)
The effects of substituents in the phenol on the regioselectivity of the ring opening of methyl- and vinylthiiranes with phenols in the presence of 3-chloro-1-propene have been studied.Increasing the electron-donating properties of the substituent in the phenol increases the amount of the isomer corresponding to cleavage of the ring in accordance with Krasurskii's rule.The reaction rate was increased considerably when carried out in highly polar aprotic solvents.
