101421-85-6

Basic information

• Product Name: 2-BROMO-3-METHYLBENZAMIDE
• Synonyms: 2-BROMO-3-METHYLBENZAMIDE
• CAS NO: 101421-85-6
• Molecular Formula: C₈H₈BrNO
• Molecular Weight: 214.05922
• Product Categories: Anilines, Amides & Amines;Bromine Compounds
• Mol File: 101421-85-6.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-BROMO-3-METHYLBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-3-METHYLBENZAMIDE(101421-85-6)
• EPA Substance Registry System: 2-BROMO-3-METHYLBENZAMIDE(101421-85-6)

Safety Data

• Hazardous Substances Data: 101421-85-6(Hazardous Substances Data)

Upstream product

• 53663-39-1 3-methyl-2-bromobenzoic acid 

Downstream Products

• 131002-06-7 2-ethenyl-3-methylbenzamide 
• 1086429-87-9 2-bromo-3-(bromomethyl)benzonitrile 
• 1268335-57-4 2-bromo-3-formylbenzyl acetate 
• 1268335-59-6 2-bromo-3-(4-hydroxybutyl)benzyl acetate 
• 1268335-60-9 2-bromo-3-(4-oxobutyl)benzyl acetate 
• 1268335-61-0 4-(3-(acetoxymethyl)-2-bromophenyl)butanoic acid 
• 1268335-62-1 methyl 4-(3-(acetoxymethyl)-2-bromophenyl)butanoate 
• 1268335-63-2 methyl 4-(3-(acetoxymethyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)butanoate 
• 91179-40-7 2-ethoxy-3-methylbenzamide 
• 1319194-52-9 6-(2-methyl-6-(4-methyloxazol-2-yl)phenyl)-3-morpholinoquinolin-2-amine 
• 1319197-02-8 2-(2-bromo-3-methylphenyl)-4-methyloxazole 
• 1268335-58-5 (E)-2-bromo-3-(4-(tetrahydro-2H-pyran-2-yloxy)but-1-enyl)benzyl acetate 
• 1268335-68-7 (E)-2-bromo-3-(3-oxobut-1-enyl)benzyl acetate 
• 263159-64-4 2-bromo-3-methyl-benzonitrile 

Relevant articles and documents

SHP2 PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF

The present disclosure relates to novel compounds including formula (X) and pharmaceutical compositions thereof, and methods for inhibiting the activity of SHP2 phosphatase with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with SHP2 deregulation with the compounds and compositions of the disclosure.

Synthesis and structure-activity relationships of novel benzoxaboroles as a new class of antimalarial agents

A series of boron-containing benzoxaborole compounds was designed and synthesized for a structure-activity relationship investigation surrounding 7-(HOOCCH2CH2)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (1) with the goal of discovering

AMINO HETEROARYL COMPOUNDS AS BETA-SECRETASE MODULATORS AND METHODS OF USE

The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, the compounds have a general Formula (I); wherein ring A, B1, B2, B3, L, R1, R2, ring Z, m and n of Formula I are defined herein. The invention also includes use of these compounds in pharmaceutical compositions for treatment, prophylactic or therapeutic, of disorders and conditions related to the activity of beta-secretase protein. Such disorders include, for example, Alzheimer's Disease (AD), cognitive deficits, cognitive impairment, schizophrenia and other central nervous system conditions related to and/or caused by the formation and/or deposition of plaque on the brain. The invention also comprises further embodiments of Formula (I), intermediates and processes useful for the preparation of compounds of Formula (I).