1014698-41-9Relevant academic research and scientific papers
Synthesis of α-CF2-mannosides and their conversion to fluorinated pseudoglycopeptides
Poulain, Florent,Serre, Anne-Lise,Lalot, Jerome,Leclerc, Eric,Quirion, Jean-Charles
, p. 2435 - 2438 (2008)
(Chemical Equation Presented) A methodology allowing the synthesis α-CF2-mannosides, based on the addition of a difluoroenoxysilane to a glycal followed by a dihydroxylation reaction, is described. The resulting 2,2-difluoro-2-mannosylacetate is converted into two pseudoglycopeptides which may act as E- and P-selectin inhibitors.
