10147-05-4 Usage
General Description
2-(quinolin-4-yl)acetamide is a synthetic chemical compound that is derived from quinoline, a heterocyclic aromatic organic compound. It is also known as quinaldine acetamide and has the molecular formula C11H10N2O. 2-(quinolin-4-yl)acetamide is often used as a building block in organic synthesis and pharmaceutical research, and has been studied for its potential medicinal properties. It has been shown to exhibit anticonvulsant and neuroprotective effects in animal studies, making it a potential candidate for the development of new drugs for the treatment of neurological disorders. Additionally, 2-(quinolin-4-yl)acetamide is considered to be a relatively safe chemical compound with low toxicity levels.
Check Digit Verification of cas no
The CAS Registry Mumber 10147-05-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,1,4 and 7 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 10147-05:
(7*1)+(6*0)+(5*1)+(4*4)+(3*7)+(2*0)+(1*5)=54
54 % 10 = 4
So 10147-05-4 is a valid CAS Registry Number.
10147-05-4Relevant articles and documents
Aryl-indolyl maleimides as inhibitors of CaMKIIδ. Part 1: SAR of the aryl region
Levy, Daniel E.,Wang, Dan-Xiong,Lu, Qing,Chen, Zheng,Perumattam, John,Xu, Yong-jin,Liclican, Albert,Higaki, Jeffrey,Dong, Hanmin,Laney, Maureen,Mavunkel, Babu,Dugar, Sundeep
, p. 2390 - 2394 (2008/09/21)
A family of aryl-substituted maleimides was prepared and studied for their activity against calmodulin dependant kinase. Inhibitory activities against the enzyme ranged from 34 nM to >20 μM and were dependant upon both the nature of the aryl group and the hydrogen bond donating potential of the maleimide ring. Key interactions with the kinase ATP site and hinge region were found to be consistent with homology modeling predictions.
