101471-73-2

Upstream product

• 109-02-4 4-methyl-morpholine 
• 6214-23-9 methyl (2Z)-3-iodoprop-2-enoate 
• 922-67-8 propynoic acid methyl ester 

Downstream Products

• 87565-78-4 methyl 2-methyl-4-morpholino-6-hydroxybenzoate 
• 74106-00-6 2-Hydroxy-4-methyl-6-morpholinobenzoesaeure-methylester 
• 83577-51-9 methyl 5-phenyl-3-morpholinopenta-2E,4E-dienoate 
• 100465-53-0 methyl 4-(1'-hydroxycyclohexanyl)-3-morpholinocrotonate 
• 83577-53-1 methyl 7-phenyl-3-morpholinohepta-2E,4E,6E-trienoate 
• 100465-54-1 methyl 3-morpholino-4-cyclohexylidenecrotonate 
• 136758-31-1 2-Morpholin-4-yl-4-(4-nitro-phenyl)-5-oxo-4,5-dihydro-indeno[1,2-b]pyran-3-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of 2-(chloro(methoxy, morpholino)methyl)-hexahydropyrimidothieno[3,2-c]azocines and tetrahydrospiro[pyrido[4,5']thieno[2,3-d]pyrimidines]

2-(Chloromethyl)-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-ones reacted with acetylenedicarboxylate ester, methyl propiolate or acetylacetylene, forming mixtures of 2-(chloromethyl)-5,6,7,10-tetrahydropyrimido[5',4':4,5]thieno[3,2-d]

An unusual Michael addition-dealkylation or elimination via the reaction of tertiary or secondary amines with a (Z)-iodoacrylate

A series of (E)-ammonium or amino acrylates have been prepared via the Michael addition of methyl (Z)-iodoacrylate and several secondary and tertiary alkylamines. Tertiary amines undergo concomitant addition-dealkylation, almost quantitatively producing (