1014977-91-3

Basic information

• Product Name: N-(4-chlorobenzyl)-N'-[2-(2-nitrophenyl)acetyl]-S-{3-[1-(triphenylmethyl)imidazol-4-yl]propyl}isothiourea
• Synonyms: N-(4-chlorobenzyl)-N'-[2-(2-nitrophenyl)acetyl]-S-{3-[1-(triphenylmethyl)imidazol-4-yl]propyl}isothiourea
• CAS NO: 1014977-91-3
• Molecular Weight: 714.288
• Mol File: 1014977-91-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-chlorobenzyl)-N'-[2-(2-nitrophenyl)acetyl]-S-{3-[1-(triphenylmethyl)imidazol-4-yl]propyl}isothiourea(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-chlorobenzyl)-N'-[2-(2-nitrophenyl)acetyl]-S-{3-[1-(triphenylmethyl)imidazol-4-yl]propyl}isothiourea(1014977-91-3)
• EPA Substance Registry System: N-(4-chlorobenzyl)-N'-[2-(2-nitrophenyl)acetyl]-S-{3-[1-(triphenylmethyl)imidazol-4-yl]propyl}isothiourea(1014977-91-3)

Safety Data

• Hazardous Substances Data: 1014977-91-3(Hazardous Substances Data)

Upstream product

• 1014977-85-5 N-(4-chlorobenzyl)-N'-(2-nitrophenylacetyl)thiourea 
• 152030-49-4 3-(1-trityl-1H-imidazol-4-yl)propan-1-ol 

Downstream Products

• 1014977-97-9 N-(4-chlorobenzyl)-S-{3-[1-(triphenylmethyl)imidazol-4-yl]propyl}isothiourea 
• 18108-55-9 1,3-dihydro-1-hydroxyindole-2-one 

Relevant articles and documents

Efficient approaches to S-alkyl-N-alkylisothioureas: Syntheses of histamine H3 antagonist clobenpropit and its analogues

(Chemical Equation Presented) S-Alkyl-N-alkylisothioureas were efficiently synthesized via synthetic approach (A) using 3-phenylpro-pionyl isothiocyanate (PPI). The utility of the approach was proved by the syntheses of clobenpropit, a potent histamine H3 antagonist, and its analogues. Alternatively, clobenpropit could be prepared via intramolecular amide cleavage (B) with use of 2-nitrophenylacetyl isothiocyanate (NPAI).