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1H-Indazole-1,5-dicarboxylic acid, 3-methyl-, 1-(1,1-dimethylethyl) 5-methyl ester, also known as TMC-435350, is a chemical compound with the molecular formula C15H18N2O4. It is a derivative of indazole and is commonly used in the field of pharmaceuticals. 1H-Indazole-1,5-dicarboxylic acid, 3-methyl-, 1-(1,1-dimethylethyl) 5-methyl ester is a potent inhibitor of the NS3/4A protease, an enzyme that plays a crucial role in the replication of the hepatitis C virus. Its chemical structure and properties make it a valuable tool in the development of new antiviral medications.

1015068-75-3

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1015068-75-3 Usage

Uses

Used in Pharmaceutical Industry:
1H-Indazole-1,5-dicarboxylic acid, 3-methyl-, 1-(1,1-dimethylethyl) 5-methyl ester is used as an antiviral agent for the treatment of hepatitis C. It functions as a potent inhibitor of the NS3/4A protease, which is essential for the replication of the hepatitis C virus. Research is ongoing to explore its potential therapeutic applications in treating this viral infection.

Check Digit Verification of cas no

The CAS Registry Mumber 1015068-75-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,1,5,0,6 and 8 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1015068-75:
(9*1)+(8*0)+(7*1)+(6*5)+(5*0)+(4*6)+(3*8)+(2*7)+(1*5)=113
113 % 10 = 3
So 1015068-75-3 is a valid CAS Registry Number.

1015068-75-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-O-tert-butyl 5-O-methyl 3-methylindazole-1,5-dicarboxylate

1.2 Other means of identification

Product number -
Other names 1-tert-Butyl 5-methyl 3-methyl-1H-indazole-1,5-dicarboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1015068-75-3 SDS

1015068-75-3Downstream Products

1015068-75-3Relevant academic research and scientific papers

Amino-substituted heterocycles, compositions thereof, and methods of treatment therewith

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Page/Page column 40, (2008/12/07)

Provided herein are Heterocyclic Compounds having the following structure: wherein R1, R2, X, Y and Z are as defined herein, compositions comprising an effective amount of a Heterocyclic Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heterocyclic Compound to a patient in need thereof.

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