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10151-02-7

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10151-02-7 Usage

General Description

N-(1,1,3,3-Tetramethylbutyl)formamide is a specialized organic chemical compound. It is a member of the class of formamides, compounds that contain a formamide group, which is a functional group that consists of a carbonyl and an amide group (NH2) linked to the same carbon atom. This chemical compound is recognized for its unique structural formulation characterized by the presence of a tetramethylbutyl group. The detailed properties, potential applications, reactivity, or health hazards related to this specific chemical compound would depend on scientific experimentation and research.

Check Digit Verification of cas no

The CAS Registry Mumber 10151-02-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,1,5 and 1 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 10151-02:
(7*1)+(6*0)+(5*1)+(4*5)+(3*1)+(2*0)+(1*2)=37
37 % 10 = 7
So 10151-02-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H19NO/c1-8(2,3)6-9(4,5)10-7-11/h7H,6H2,1-5H3,(H,10,11)

10151-02-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(2,4,4-trimethylpentan-2-yl)formamide

1.2 Other means of identification

Product number -
Other names tert-Octylformamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10151-02-7 SDS

10151-02-7Relevant articles and documents

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Henbest,H.B.,Stratford,M.J.W.

, p. 995 - 996 (1966)

-

Moffat et al.

, p. 4058 (1962)

Isocyanides as influenza A virus subtype H5N1 wild-type M2 channel inhibitors

Wu, Shuwen,Huang, Jing,Gazzarrini, Sabrina,He, Si,Chen, Lihua,Li, Jun,Xing, Li,Li, Chufang,Chen, Ling,Neochoritis, Constantinos G.,Liao, George P.,Zhou, Haibing,D?mling, Alexander,Moroni, Anna,Wang, Wei

, p. 1837 - 1845 (2015/11/10)

Basic bulky amines such as amantadine are well-characterized M2 channel blockers, useful for treating influenza. Herein we report our surprising findings that charge-neutral, bulky isocyanides exhibit activities similar to - or even higher than - that of amantadine. We also demonstrate that these isocyanides have potent growth inhibitory activity against the H5N1 virus. The -NH2 to -N≡C group replacement within current anti-influenza drugs was found to give compounds with high activities at low-micromolar concentrations. For example, a tenfold improvement in potency was observed for 1-isocyanoadamantane (27), with an EC50 value of 0.487 μm against amantadine-sensitive H5N1 virus as determined by both MTT and plaque-reduction assays, without showing cytotoxicity. Furthermore, the isocyanide analogues synthesized in this study did not inhibit the V27A or S31N mutant M2 ion channels, according to electrophysiology experiments, and did not exhibit activity against amantadine-resistant virus strains. Charge-neutral bulky isocyanides were found to exhibit antiviral activities similar to - or even higher than - that of amantadine. Moreover, we demonstrated that these isocyanides have potent growth inhibitory activity against the wild-type H5N1 virus. The NH2 to N≡C group replacement within current anti-influenza drugs was found to result in compounds with low-micromolar activities.

Isocyanide-based multicomponent [2+2+1]-cycloaddition strategy to construct functionalized spirocyclic oxindoles

Jie, Haohua,Li, Jian,Li, Chunju,Jia, Xueshun

supporting information, p. 2274 - 2278 (2012/10/29)

Isocyanide-based three-component [2+2+1]-cycloaddition reactions from isocyanides, activated alkynes, and isatylidene malononitriles were investigated to provide a new access to spirocyclic oxindole with five-membered carbon rings. The displacement of isatylidene malononitrile with oxindolylideneacetate essentially results in opposite regioselectivity, which adds to its attractiveness. Georg Thieme Verlag Stuttgart ? New York.

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