1015186-70-5Relevant articles and documents
Synthesis of vinyl-functionalized oxazoles by olefin cross-metathesis
Hoffman, Thomas J.,Rigby, James H.,Arseniyadis, Stellios,Cossy, Janine
, p. 2400 - 2403 (2008/09/18)
(Chemical Equation Presented) A ruthenium-based catalyzed olefin cross-methathesis reaction involving 2- and 4-vinyl-functionalized oxazoles was developed. A wide range of olefinic partners was coupled in good to excellent yields and high stereoselectivities under mild conditions. This methodology offers new opportunities for the synthesis of a plethora of biologically active natural products.