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1015252-19-3

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1015252-19-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1015252-19-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,1,5,2,5 and 2 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1015252-19:
(9*1)+(8*0)+(7*1)+(6*5)+(5*2)+(4*5)+(3*2)+(2*1)+(1*9)=93
93 % 10 = 3
So 1015252-19-3 is a valid CAS Registry Number.

1015252-19-3Downstream Products

1015252-19-3Relevant articles and documents

Synthesis of 3-aminopropyl β-glycoside of sialyl-3'-lactose and derived neoglycoconjugates as a tumor vaccine prototype and artificial antigens for the control of immune response

Khatuntseva,Yudina,Tsvetkov,Grachev,Stepanenko,Vlasenko,Lvov,Nifantiev

, p. 2095 - 2102 (2006)

Starting from the biotechnologically available trisaccharide sialyl-3'-lactose, representing the carbohydrate portion of the tumor-associated ganglioside GM3, the corresponding 3-aminopropyl β-glycoside (1) and 3-(4-maleimidobutanoylamino)propyl glycoside were synthesized. The reaction of the latter with a thiolated derivative of the Megathura crenulata hemocyanine (KLH) afforded a carbohydrate-protein conjugate, a tumor vaccine prototype containing about 330 trisaccharide ligands attached to KLH. N-Stearoylation of ligand 1 gave the model neoglycolipid for comparative study of the activity of mono-and polyvalent immunogens and the natural ganglioside GM3. A monovalent conjugate, in which ligand 1 is linked to biotin through an oligo(ethylene glycol) spacer and a polyvalent conjugate with a polyacrylamide carrier were also prepared. These conjugates are meant as covering antigens to assess the specificity and efficiency of the immune response in the ELISA assay.

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