101527-44-0

Basic information

• Product Name: 1-[(2R,4S,5R)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-4-hydroxy-tetrahydro-furan-2-yl]-5-dibromomethyl-1H-pyrimidine-2,4-dione
• CAS NO: 101527-44-0
• Molecular Weight: 638.428
• Mol File: 101527-44-0.mol

Chemical Properties

• CAS DataBase Reference: 1-[(2R,4S,5R)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-4-hydroxy-tetrahydro-furan-2-yl]-5-dibromomethyl-1H-pyrimidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(2R,4S,5R)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-4-hydroxy-tetrahydro-furan-2-yl]-5-dibromomethyl-1H-pyrimidine-2,4-dione(101527-44-0)
• EPA Substance Registry System: 1-[(2R,4S,5R)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-4-hydroxy-tetrahydro-furan-2-yl]-5-dibromomethyl-1H-pyrimidine-2,4-dione(101527-44-0)

Safety Data

• Hazardous Substances Data: 101527-44-0(Hazardous Substances Data)

Upstream product

• 50-89-5 thymidine 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 101527-40-6 5'-O-tert-butyldiphenylsilylthymidine 

Downstream Products

• 101527-46-2 α,α-difluorothymidine 
• 101527-43-9 5'-O-tert-Butyldiphenylsilyl-2'-deoxy-5-difluoromethyluridine 

Relevant articles and documents

Synthesis of 2'-Deoxy-5-monofluoromethyluridine (FTDR) and 2'-Deoxy-5-difluoromethyluridine (F2TDR)

The synthesis of potential anticancer and antitumour nucleosides, 2'-deoxy-5-monofluoromethyluridine (FTDR) and 2'-deoxy-5-difluoromethyluridine (F2TDR) was achieved in four steps from thymidine including monosilylation with t-butyldiphenylsilyl chloride,