1015414-82-0

Basic information

• Product Name: (2,5-difluoro-4-nitrophenyl)(2-fluoro-5-methoxyphenyl)methanone
• Synonyms: (2,5-difluoro-4-nitrophenyl)(2-fluoro-5-methoxyphenyl)methanone
• CAS NO: 1015414-82-0
• Molecular Weight: 311.217
• Mol File: 1015414-82-0.mol

Chemical Properties

• CAS DataBase Reference: (2,5-difluoro-4-nitrophenyl)(2-fluoro-5-methoxyphenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2,5-difluoro-4-nitrophenyl)(2-fluoro-5-methoxyphenyl)methanone(1015414-82-0)
• EPA Substance Registry System: (2,5-difluoro-4-nitrophenyl)(2-fluoro-5-methoxyphenyl)methanone(1015414-82-0)

Safety Data

• Hazardous Substances Data: 1015414-82-0(Hazardous Substances Data)

Upstream product

• 2105-61-5 1,2,4-trifluoro-5-nitrobenzene 
• 105728-90-3 2-fluoro-5-methoxybenzaldehyde 

Downstream Products

• 1296257-46-9 5-allyloxy-2,2'-difluoro-5'-methoxy-4-nitrobenzophenone 
• 1296257-37-8 5'-hydroxy-4-nitro-2,2',5-trifluorobenzophenone 
• 1296257-67-4 6-(5-benzyloxy-2-hydroxybenzoyl)-5,8-dihydroxy-2,2-dimethylchromene 
• 1296257-62-9 6-(2-allyloxy-5-benzyloxybenzoyl)-5,8-diallyloxy-2,2-dimethylchromene 
• 1296257-58-3 6-(5-benzyloxy-2-fluorobenzoyl)-2,2-dimethyl-5-fluoro-8-allyloxychromene 
• 1296257-66-3 5-allyloxy-5'-benzyloxy-2,2'-difluoro-4-(1,1-dimethylpropargyloxy)benzophenone 
• 1296257-65-2 5-allyloxy-5'-benzyloxy-2,2'-difluoro-4-hydroxybenzophenone 
• 1296257-57-2 5-allyloxy-5'-benzyloxy-2,2'-difluoro-4-nitrobenzophenone 
• 1296257-55-0 5,8-dihydroxy-6-(2-hydroxy-5-methoxybenzoyl)-2,2-dimethylchromene 
• 1296257-54-9 6-(2-allyloxy-5-methoxybenzoyl)-5,8-diallyloxy-2,2-dimethylchromene 
• 1296257-49-2 8-allyloxy-5-fluoro-6-(2-fluoro-5-methoxybenzoyl)-2,2-dimethylchromene 
• 1296257-48-1 5-allyloxy-2,2'-difluoro-4-(1,1-dimethylpropargyloxy)-5'-methoxybenzophenone 
• 1296257-47-0 5-allyloxy-2,2'-difluoro-4-hydroxy-5'-methoxybenzophenone 
• 1296257-45-8 5,8,17-dimethoxy-2,2-dimethyl-6-(2-methoxy-5-tosyloxybenzoyl)chromene 

Relevant articles and documents

N-heterocyclic carbene-catalyzed nucleophilic aroylation of fluorobenzenes

(Chemical Equation Presented) In N-heterocyclic carbene (NHCs) catalyzed nucleophilic substitution of fluorobenzenes, fluoro groups are replaced by aroyl groups, which are derived from aromatic aldehydes. 1,3,4,5-Tetramethylimidazol- 2-ylidene is found to be an efficient catalyst. The catalyst loading can be reduced to 1 mol % without a significant decrease in the product yields. Polysubstituted benzophenones are synthesized from fluorobenzenes and benzaldehydes by the NHC-catalyzed aroylation.

Recyclable polyetheretherketone fiber-supported N-heterocyclic carbene catalysts for nucleophilic acylation of fluorobenzenes

We report for the first time a novel support of polyetheretherketone fiber for the synthesis of recyclable N-heterocyclic carbene (NHC) catalysts. The fiber catalysts were verified in nucleophilic acylation of fluorobenzenes with superior catalytic activities, and successfully recycled by a tiny pair of tweezers over 21 cycles with minimal loss of performance.

Total Synthesis of Termicalcicolanone A via Organocatalysis and Regioselective Claisen Rearrangement

A total synthesis of an anticancer xanthone natural product termicalcicolanone A utilizing multiple nucleophilic aromatic substitutions and pericyclic reactions has been developed. The pyrano[3,2-b]xanthen-6-one scaffold was constructed via NHC-catalyzed

Xanthone natural products via N -heterocyclic carbene catalysis: Total synthesis of atroviridin

The total synthesis of atroviridin has been accomplished by a linear route involving the N-heterocyclic carbene (NHC)-catalyzed aroylation of the fluorobenzene derivative, Claisen cyclization of the O-propargylated benzophenones, and intramolecular 1,4-addition of the quinone intermediates. The result provides a viable route to xanthone natural products.