1015422-73-7Relevant articles and documents
Structural aspects of nucleation inhibitors for diastereomeric resolutions and the relationship to Dutch resolution
Leeman, Michel,Brasile, Giuseppina,Gelens, Edith,Vries, Ton,Kaptein, Bernard,Kellogg, Richard
, p. 1287 - 1290 (2008/12/22)
You say you want a resolution: Nucleation inhibitors for the resolution of diastereomers by selective crystallization have been designed and tested. The resolution of racemic 3-methoxyphenylethylamine was optimized with (S)-mandelic acid as the resolving agent (see scheme). Multifunctional inhibitors are particularly effective. (Chemical Equation Presented).