1015486-71-1

Basic information

• Product Name: 3-(3-fluoro-phenyl)-oxirane-2-carbaldehyde
• Synonyms: 3-(3-fluoro-phenyl)-oxirane-2-carbaldehyde
• CAS NO: 1015486-71-1
• Molecular Weight: 166.152
• Mol File: 1015486-71-1.mol

Chemical Properties

• CAS DataBase Reference: 3-(3-fluoro-phenyl)-oxirane-2-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-fluoro-phenyl)-oxirane-2-carbaldehyde(1015486-71-1)
• EPA Substance Registry System: 3-(3-fluoro-phenyl)-oxirane-2-carbaldehyde(1015486-71-1)

Safety Data

• Hazardous Substances Data: 1015486-71-1(Hazardous Substances Data)

Upstream product

• 56578-38-2 3-fluorocinnamaldehyde 
• 42291-83-8 (E)-3-(3-fluorophenyl)acrylaldehyde 

Downstream Products

• 693220-51-8 (2S,3S)-3-(3-fluorophenyl)-2-(hydroxymethyl)oxirane 

Relevant articles and documents

Asymmetric epoxidation of α,β-unsaturated aldehydes catalyzed by a spiro-pyrrolidine-derived organocatalyst

The asymmetric epoxidation of α,β-unsaturated aldehydes, catalyzed by a spiro-pyrrolidine (SPD)-derived organocatalyst, has been accomplished with good diastereoselectivities (up to dr >20:1) and with high to excellent enantioselectivities (up to 99% ee).

Asymmetric counteranion-directed catalysis for the epoxidation of enals

(Chemical Equation Presented) A new mode of chiral anion catalysis: A powerful chiral-counteranion strategy for catalytic asymmetric epoxidations using the newly discovered catalyst 1 has been applied to the epoxidation of α,β-unsaturated aldehydes together with tert-butyl hydroperoxide as the oxidant (see scheme). Remarkably, this system provides the corresponding epoxides in high diastereo- and enantioselectivity for both di- and trisubstituted enals.