10156-50-0

Basic information

• Product Name: Piperidine, 1-(2,6-dinitrophenyl)-
• CAS NO: 10156-50-0
• Molecular Formula: C11H13N3O4
• Molecular Weight: 251.242
• Mol File: 10156-50-0.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Piperidine, 1-(2,6-dinitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 1-(2,6-dinitrophenyl)-(10156-50-0)
• EPA Substance Registry System: Piperidine, 1-(2,6-dinitrophenyl)-(10156-50-0)

Safety Data

• Hazardous Substances Data: 10156-50-0(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 606-21-3 1-chloro-2,6-dinitrobenzene 
• 32024-96-7 2,6-dinitrophenyl phenyl ether 
• 88-73-3 2-Chloronitrobenzene 
• 573-55-7 2-fluoro-1,3-dinitrobenzene 
• 3535-67-9 2,6-dinitroanisole 
• 120952-14-9 2-(2,6-dinitrophenoxy)-N-ethylpyridinium tetraphenylborate 

Downstream Products

• 1355961-94-2 2-piperidin-1-yl-benzene-1,3-diamine 
• 1356016-28-8 3-(3-amino-2-piperidin-1-yl-phenylamino)-propan-1-ol 

Relevant articles and documents

A mechanistic viewpoint of the reaction between 1-fluoro-2,6-dinitrobenzene and alicyclic amines in the ethyl acetate-chloroform system

A study was made of the influence of temperature on the reactions between 1-fluoro-2,6-dinitrobenzene and each of the secondary amines pyrrolidine, piperidine and homopiperidine (hexahydro-1H-azepine), carried out in ethyl acetate-chloroform binary solvent mixtures. It involved the analysis of both global activation parameters and the corresponding Arrhenius plots from the kA values at three amine concentrations. These values were obtained by carrying out the reactions at 5, 15, 25, 40 and 50°C over the whole range of chloroform mole fraction. The analysis of Arrhenius lines allowed us to prove the existence of isokinetic relationships, which were used as a diagnostic tool in order to infer a changeover in the nature of the rate-determining transition state as a function of solvent composition. The experimental evidence together with theoretical quantum mechanical calculations suggest that the reactions with the secondary amines explored carried out in pure ethyl acetate and ethyl acetate-chloroform solvent mixture at XCHCl3, = 0.1 and in some cases also at XCHCl3 = 0.3 proceed via the formation of a six-membered orientated dipolar aggregate in which the specific base-general acid (SB-GA) mechanism may take place. The reactions carried out in the remaining solvent mixtures evolve towards the classical SB-GA mechanism. Copyright

PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS

Compounds of the formula I or II: wherein X, m, Ar, R1 and R2 are as defined herein. The subject compounds are useful for treatment of IRAK-mediated conditions.

Effects of ortho- and para-ring activation on the kinetics of S NAr reactions of 1-chloro-2-nitro- and 1-phenoxy-2-nitrobenzenes with aliphatic amines in acetonitrile

Rate constants are reported for reaction of 4-substituted 1-chloro-2,6-dinitrobenzenes 1, 6-substituted 1-chloro-2,4-dinitrobenzenes 2, and some of the corresponding 1-phenoxy derivatives, 3 and 4, with n-butylamine, pyrrolidine and pi-peridine in acetoni