1015782-62-3Relevant articles and documents
Synthesis of perfluoro[2.2]paracyclophane
Dolbier Jr., William R.,Xie, Puhui,Zhang, Lianhao,Xu, Wei,Chang, Ying,Abboud, Khalil A.
, p. 2469 - 2472 (2008)
(Chemical Equation Presented) A synthesis of perfluoro[2.2]paracyclophane has been sought ever since the partially fluorinated octafluoro[2.2]- paracyclophane (AF4) was prepared and its chemistry studied. This compound has now been prepared in 39% yield from the precursor, 1,4-bis(chlorodifluoromethyl) -2,3,5,6-tetrafluorobenzene by its reaction with Zn when heated in acetonitrile at 100°C. Two preparations of the precursor, first from 1,4-dicyano-2,3,5,6- tetrachlorobenzene and an improved method beginning from 1,2,4,5- tetrachlorobenzene, are also described as are key comparisons to our related synthesis of AF4.