101583-01-1

Basic information

• Product Name: 2-cyano-2-phenyldiethyl adipate
• Synonyms: 2-cyano-2-phenyldiethyl adipate
• CAS NO: 101583-01-1
• Molecular Weight: 303.358
• Mol File: 101583-01-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-cyano-2-phenyldiethyl adipate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-cyano-2-phenyldiethyl adipate(101583-01-1)
• EPA Substance Registry System: 2-cyano-2-phenyldiethyl adipate(101583-01-1)

Safety Data

• Hazardous Substances Data: 101583-01-1(Hazardous Substances Data)

Upstream product

• 2969-81-5 Ethyl 4-bromobutyrate 
• 4553-07-5 ethyl phenylcyanoacetate 
• 3153-36-4 4-chloro-butyric acid ethyl ester 

Downstream Products

• 167398-59-6 6-ethoxycarbonyl-6-phenylazepin-2-one 

Relevant articles and documents

New pyrrolidin-, piperidin- and azepin-2-oxocarboxylic acid esters are preferential M1, M3 muscarinic antagonists. Synthesis and bronchospasmolytic activity

A series of new 3-tropanol and 3-quinuclidinol esters of phenyl-substituted pyrrolidin-, piperidin- and azepin-2-oxocarboxylic acid were synthesized and tested for antimuscarinic activity. The compounds showed a preferential in vitro activity at M1 and M3 receptor subtypes and an interesting activity profile in vivo. A potential use as selective bronchospasmolytic agents has been suggested for selected compounds.

New R(-) 3-quinuclidinol derivatives

Pharmacologically active R(-) 3-quinuclidinol derivatives are described which are muscarinic receptor blocking agents useful for the treatment of gastrointestinal and respiratory tract disorders of the following formula (I) wherein, R represents a linear