1016-35-9 Usage
General Description
2-(5-chloro-1H-indol-3-yl)-2-oxoacetamide is a chemical compound with a molecular formula of C10H7ClN2O2. It is an indole derivative with a chloro substituent at the 5-position and a carbonyl group at the 2-position. 2-(5-chloro-1H-indol-3-yl)-2-oxoacetamide is commonly used in organic synthesis and medicinal chemistry as a building block for the development of various pharmaceuticals and bioactive molecules. Its structure and reactivity make it a valuable tool for the creation of novel compounds with potential therapeutic applications. Additionally, its indole moiety gives it the potential for various biological activities, making it a valuable target for research and drug discovery efforts.
Check Digit Verification of cas no
The CAS Registry Mumber 1016-35-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,1 and 6 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1016-35:
(6*1)+(5*0)+(4*1)+(3*6)+(2*3)+(1*5)=39
39 % 10 = 9
So 1016-35-9 is a valid CAS Registry Number.
1016-35-9Relevant academic research and scientific papers
A versatile linkage strategy for solid-phase synthesis of N,N-dimethyltryptamines and β-carbolines
Wu, Tom Y. H.,Schulte, Peter G.
, p. 4033 - 4035 (2007/10/03)
(matrix presented) Various tryptamines are captured by a vinylsulfonylmethyl polystyrene resin, generating a safety-catch linkage. β-Carbolines can be formed from 4 by a Pictet-Spengler reaction with the introduction of R1. Tryptamine 4 can also be derivatized by acylation or copper-mediated coupling to introduce R2. If X = Br, Suzuki coupling can be used to introduce R3. After derivatization, the indole derivatives are activated with methyl iodide and released under mild basic condition.
