10162-58-0 Usage
General Description
7-methylguanosine-5'-monophosphate is a chemical compound consisting of a guanosine molecule with a methyl group attached to the seventh carbon atom. It is a monophosphate ester, meaning that it has one phosphate group attached to the 5' carbon of the ribose ring. 7-methylguanosine-5'-monophosphate is important in biological processes such as RNA metabolism and protein synthesis. It is often found as a component of transfer RNA (tRNA), where it plays a role in stabilizing the structure of the tRNA molecule and in facilitating the proper binding of amino acids during protein synthesis. Additionally, 7-methylguanosine-5'-monophosphate has also been studied for its potential role in cancer therapy, as it may be involved in the regulation of cell growth and proliferation.
Check Digit Verification of cas no
The CAS Registry Mumber 10162-58-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,1,6 and 2 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 10162-58:
(7*1)+(6*0)+(5*1)+(4*6)+(3*2)+(2*5)+(1*8)=60
60 % 10 = 0
So 10162-58-0 is a valid CAS Registry Number.
10162-58-0Relevant articles and documents
Regio-selective synthesis of polyazacyclophanes incorporating a pendant group as potential cleaving agents of mRNA 5′-cap structure
Zhang, Zhibo,Mikkola, Satu,Lonnberg, Harri
, p. 11716 - 11723 (2008/03/14)
A terpyridine or an imidazole unit has been tethered to an N-protected polyazacyclophane to give the appropriate N-monofunctionalized polyazacyclophane. After mild deprotection, four polyazacyclophanes incorporating a pendant group were obtained in satisf
The Cu2+-promoted cleavage of mRNA 5'-cap analogs: A kinetic study with p1(7-methylguanosin-5'-yl) p3-(nucleosid-5'-yl) triphospates and p1- (7-methylguanosin-5'-yl) p4-(guanosin-5'-yl) tetraphosphate
Wieczorek, Zbigniew,Darzynkiewicz, Edward,Kuusela, Satu,Loennberg, Harri
, p. 11 - 21 (2007/10/03)
A kinetic study on the cleavage of a number of mRNA 5'-cap analogs, m7GpppN and m7GppppG, with Cu2+ aquo ion has been performed. Time- dependent product distributions at various pH and metal ion concentrations have been determined by capillary zone electrophoresis, and these data have been used to calculate the rate constants for various parallel reactions of the breakdown of the cap analogs.
