101620-47-7Relevant academic research and scientific papers
Pyridylthiazolidinecarboxylic acid amide derivatives, their preparation and their therapeutic uses
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, (2008/06/13)
New pyridylthiazolinecarboxylic acid amide compounds have been found to have a valuable combination of antiallergic and antiasthmatic activities with an antagonist activity against Platelet Activating Factor.
Amide derivatives and 5-lipoxygenase inhibitors containing the same as an active ingredient
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, (2008/06/13)
According to the invention, there are provided novel amide derivatives and 5-lipoxygenase inhibitors containing the same as an effective ingredient. The above-mentioned compounds of the invention have been demonstrated to posses 5-lipoxygenase-inhibiting activities. These compounds can inhibit the production of leucotrienes such as LTC4 and LTD4 which are allergy-inducing factors by inhibiting the activity of 5-lipoxygenase. Accordingly, the amide derivatives can be used as 5-lipoxygenase inhibitors effective for allergic asthma, allergic rhinitis and the like.
