1016258-20-0Relevant academic research and scientific papers
Diastereoselective synthesis of cyclic β2,3-amino acids utilizing 4-substituted-1,3-oxazinan-6-ones
Sleebs, Brad E.,Nguyen, Nghi H.,Hughes, Andrew B.
, p. 6275 - 6284 (2013/07/27)
The 4-substituted-1,3-oxazinan-6-one scaffold is a versatile synthon enabling access to a diverse array of β-amino acid derivatives. In this study, the synthetic utility of the 1,3-oxazinan-6-one is expanded to include the diastereoselective synthesis of
Synthesis and evaluation of enantiomeric purity of protected α-amino and peptide aldehydes
Mindt, Thomas,Michel, Urs,Dick
, p. 1960 - 1968 (2007/10/03)
The synthesis of enantiomerically pure Ac-Tyr-Val-Ala-Asp(O'Bu)-H dimethyl acetal ((S)-1) is reported, a protected tetrapeptide C-terminal aldehyde belonging to a class of potent, reversible inhibitors of cysteine proteases (e.g., interleukin-1β-convertin
