101666-51-7Relevant academic research and scientific papers
Chemical Modification of Erythromycins. X. Removal of Benzyloxycarbonyl and 2-Chlorobenzyl Groups of Erythromycin Derivatives by Use of Catalytic Transfer Hydrogenation
Watanabe, Yoshiaki,Kashimura, Masato,Asaka, Toshifumi,Adachi, Takashi,Morimoto, Shigeo
, p. 761 - 768 (2007/10/02)
The benzyloxycarbonyl and the 2-chlorobenzyl groups of erythromycin derivatives were easily removed by catalytic transfer hydrogenation (CTH).Their deprotection reaction was dependent on both the hydrogen donor and the solvent for use.Application of CTH to removal of the protective groups is discussed.
