101669-84-5

Upstream product

• 136755-33-4 threo-5-(α-t-butoxycarbonylamino)benzyl-3-chloro-2-isoxazoline 
• 91230-12-5 (1-phenyl-allyl)-carbamic acid tert-butyl ester 
• 4393-21-9 1-(phenyl)allylamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 136755-39-0 threo-3-methoxy-5-(α-t-butoxycarbonylamino)benzyl-2-isoxazoline 
• 136755-33-4 erythro-5-(α-t-butoxycarbonylamino)benzyl-3-chloro-2-isoxazoline 
• 136755-39-0 erythro-3-methoxy-5-(α-t-butoxycarbonylamino)benzyl-2-isoxazoline 

Relevant academic research and scientific papers

Synthesis of DL-Statine and DL-4-Amino-3-hydroxy-4-phenylbutanoic Acids via the Isoxazoline Route

1,3-Dipolar cycloaddition of chloronitrile oxide to N-allyltrichloroacetamides and subsequent reductive cleavage of the 3-methoxy-substituted isoxazolines gives methyl 3-hydroxy-4-trichloroacetamido esters which by acidic hydrolysis give the corresponding

4-AMINOBUTANOIC ACID DERIVATIVES, PROCESS OF PREPARATION AND USE THEREOF

The invention relates to new (4S)-4-aminobutanoic acid derivatives of general formula: STR1 in which: R represents an N-protective group, R 1 represents hydrogen, an alkali metal atom such as lithium, sodium or potassium or a liabile group, R.