1016901-85-1Relevant academic research and scientific papers
Potent inhibitors of the Hedgehog signaling pathway
Brunton, Shirley A.,Stibbard, John H. A.,Rubin, Lee L.,Kruse, Lawrence I.,Guicherit, Oivin M.,Boyd, Edward A.,Price, Steven
, p. 1108 - 1110 (2008)
A small family of phenyl quinazolinone ureas is reported as potent modulators of Hedgehog protein function. Preliminary SAR studies of the urea substituent led to a nanomolar Hedgehog antagonist.
