101692-77-7Relevant academic research and scientific papers
Synthesis of Cyclopentenones with C4-Quaternary Stereocenters via Stereospecific [3,3]-Sigmatropic Rearrangement and Applications in Total Synthesis of Sesquiterpenoids
Zhou, Weiping,Voituriez, Arnaud
supporting information, p. 17348 - 17353 (2021/11/12)
A cationic gold(I)-catalyzed asymmetric [3,3]-sigmatropic rearrangement of sulfonium leads after cyclization to cyclopentenones with a C4-quaternary stereocenter. Starting with simple vinyl sulfoxides and propargyl silane, numerous compounds were isolated
Chiral Bicyclic Lactams for Asymmetric Synthesis of Quaternary Carbons. The Total Synthesis of (-)-α-Cuparenone
Meyers, A. I.,Lefker, Bruce A.
, p. 1541 - 1544 (2007/10/02)
An asymmetric synthesis of the title compounds has been achieved in >98percent ee using chiral bicyclic lactams 14 derived from (S)-valinol and γ-keto acids.Thus, cyclocondensation of racemic 2-p-tolyl-4-oxopentanoic acid with (S)-valinol gave a 1:1 mixtu
