1017079-86-5Relevant articles and documents
A novel synthesis of isoflavones via copper(I)-catalyzed intramolecular cyclization reaction
Li, Qiu-Lian,Liu, Qi-Lun,Ge, Zhi-Yuan,Zhu, Yong-Ming
experimental part, p. 1304 - 1309 (2011/09/15)
Isoflavone derivatives were synthesized via intramolecular cyclization of 3-(2-bromophenyl)-3-oxopropanal derivatives, using CuI as the catalyst, 2-picolinic acid (=pyridine-2-carboxylic acid) as the ligand, K 2CO3 as the base, and DMF as the solvent, in up to 96% yield. The synthesis is functional group-tolerant. Copyright