10172-69-7

Upstream product

• 1076-38-6 4-hydroxy[1]benzopyran-2-one 
• 552-89-6 2-nitro-benzaldehyde 
• 612-25-9 2-Nitrobenzyl alcohol 
• 22105-09-5 4‐hydroxycoumarin 

Downstream Products

• 13463-01-9 7-(2-nitrophenyl)-7H-bis-[1]benzopyrano[4,3-b:3',4'-c]pyran-6,8-dione 
• 138188-45-1 4-hydroxy-3-<(2-nitrophenyl)methyl>-2H-1-benzopyran-2-one 

Relevant academic research and scientific papers

Synthesis of biscoumarins from 4-hydroxycoumarin and aromatic aldehydes - A comparative assessment of percentage yield under thermal and microwave-assisted conditions

A convenient synthesis of various biscoumarins by condensing a series of aldehydes with 4-hydroxycoumarin under microwave irradiation is reported for the first time along with a comparative account of the syntheses under conventional conditions. The react

Sulfated titania catalyzed water mediated efficient synthesis of dicoumarols - A green approach

An efficient, mild, and environmental friendly method has been developed for the synthesis of dicoumarols in water over Lewis and Bronsted acid catalyst sulfated titania (TiO2/SO42-). The method involves the condensation of various aromatic and aliphatic aldehydes with 4-hydroxycoumarin. It affords the corresponding product in high yield with short reaction times employing a very low loading of catalyst. The catalyst was reused several times without significant change in activity.

Friedel-Crafts alkylation of 4-hydroxycoumarin over silica-bonded 1,4-diaza-bicyclo[2.2.2] octane-sulfonic acid chloride as nanostructured heterogeneous catalyst

A novel nanostructured heterogeneous catalyst, namely silica-bonded 1,4-diaza-bicyclo[2.2.2]octane-sulfonic acid chloride (SBDBSAC), has been synthesized and fully characterized by several techniques, including Fourier transform infrared spectroscopy (FTI

An unexpected tetracyclic product isolated during the synthesis of biscoumarins catalyzed by [MIM(CH2)4SO3H] [HSO4]: Characterization and X-ray crystal structure of 7-(2-hydroxy-4-oxo-4H-chromen-3-yl)-6H,7H-chro

Under solvent-free conditions and in the presence of 3-methyl-1-(4-sulfonic acid)butylimidazolium hydrogen sulfate [MIM(CH2)4SO 3H][HSO4], a Br?nsted acidic ionic liquid, the reaction of aromatic aldehydes with

Efficient synthesis of bis(indolyl)methanes, bispyrazoles and biscoumarins using 4-sulfophthalic acid

4-Sulfophthalic acid (4-H3SPA) solution 50?wt% in H2O has been effectively catalyzed the synthesis of a series of biologically relevant bis(indolyl)methanes by the electrophilic substitution of indole derivatives on aldehyde compound

Tetramethylguanidium-based ionic liquids as efficient and reusable catalysts for the synthesis of biscoumarin at room temperature

In this work, a basic ionic liquid, tetramethylguanidium acetate ([TMG][Ac]), was found to be an efficient catalyst for the one-pot preparation of biscoumarins through a domino Knoevenagel-Michael reaction at room temperature. This novel catalytic system

Click chemistry-inspired design, synthesis, and molecular docking studies of biscoumarin derivatives using carbon-based acid catalyst

A green and eco-benign synthesis of biscoumarin derivatives using carbon sulfonic acid, a solid support catalyst has been described. The reaction involved a one-pot two-component reaction of 4-hydroxycoumarin and aldehyde using carbon sulfonic acid involv

Sulfonic acid-functionalized mesoporous silica nanoparticles (SAMSNs): A recoverable heterogeneous acid catalyst for green synthesis of dicoumarols

Sulfonic acid-functionalized mesoporous silica nanoparticles (SAMSNs) have been used as a highly efficient and recoverable heterogeneous acid catalyst for green synthesis of dicoumarols by reaction of different aldehydes with 4-hydroxycoumarin in aqueous

Synthesis, toxicological, and pharmacological assessment of some oximes and aldehyde condensation products of 4-hydroxycoumarin

The synthesis of condensation products of 4-hydroxycoumarin and nitro- substituted aromatic aldehydes as well as oximes of drugs with anticoagulant activity is described. The acute toxicity of the compound was studied in mice by oral and intraperitoneal a

Ni0 NPs anchored on acid-activated montmorillonite (Ni0-Mont) as a highly efficient and reusable nanocatalyst for synthesis of biscoumarins and bisdimedones

Ni0 nanoparticles were immobilized on acid-activated montmorillonite (Ni0-Mont) by anchoring Ni(OAc)2·4H2O on modified micro/mesoporous montmorillonite followed by reduction with ethylene glycol. The prepared cl