10172-90-4Relevant articles and documents
Syntheses of the plant auxin conjugate 2-O-(indole-3-acetyl)-myo-inositol IAInos
Silva, Saúl,Ascenso, Osvaldo S.,Louren?o, Eva C.,Archer, Margarida,Maycock, Christopher D.,Ventura, M. Rita
, p. 6860 - 6864 (2018)
The plant hormone conjugate 2-O-(indole-3-acetyl)-myo-inositol (IAInos) has been selectively prepared for the first time by two routes from myo-inositol. One of the syntheses depended upon the construction of the 3-indoleacetyl group by a Fischer indole synthesis on an unreactive axial hydroxyl group, while the other via a direct acylation of the equatorially orientated hydroxy group created by conformational constraint of the cyclohexane ring. The latter synthesis produced IAInos in 5 steps and 29% overall yield.