1017238-05-9

Basic information

• Product Name: tert-butyl{[(1S,3S)-3-methoxy-1-propylhex-5-enyl]oxy}diphenylsilane
• Synonyms: tert-butyl{[(1S,3S)-3-methoxy-1-propylhex-5-enyl]oxy}diphenylsilane
• CAS NO: 1017238-05-9
• Molecular Weight: 410.672
• Mol File: 1017238-05-9.mol

Chemical Properties

• CAS DataBase Reference: tert-butyl{[(1S,3S)-3-methoxy-1-propylhex-5-enyl]oxy}diphenylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl{[(1S,3S)-3-methoxy-1-propylhex-5-enyl]oxy}diphenylsilane(1017238-05-9)
• EPA Substance Registry System: tert-butyl{[(1S,3S)-3-methoxy-1-propylhex-5-enyl]oxy}diphenylsilane(1017238-05-9)

Safety Data

• Hazardous Substances Data: 1017238-05-9(Hazardous Substances Data)

Upstream product

• 1017238-04-8 (4S,6S)-6-{[tert-butyl(diphenyl)silyl]oxy}non-1-en-4-ol 
• 420-37-1 trimethoxonium tetrafluoroborate 

Relevant articles and documents

Formal total synthesis of neopeltolide

A concise synthesis of the core structure of the macrolide neopeltolide was develop featuring a Prins cyclization to fashion the pyran ring. Key steps in the synthesis of aldehyde 16 were a Leiqhton allylation and a Feringa-Minnaard asymmetric methyl cuprate addition to an unsaturated thioester. For lactonization, a classical Yamaguchin macrolactonization was used. The longest linear sequence consists of 17 steps providing lactone 26 with an overall yield of 23%.