10173-72-5

Basic information

• Product Name: 6-methyl-2-(2-nitrophenyl)-1H-benzimidazole
• Synonyms: 1H-benzimidazole, 5-methyl-2-(2-nitrophenyl)-; 5-Methyl-2-(2-nitrophenyl)-1H-benzimidazole
• CAS NO: 10173-72-5
• Molecular Formula: C₁₄H₁₁N₃O₂
• Molecular Weight: 253.256
• Mol File: 10173-72-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 491.3°C at 760 mmHg
• Flash Point: 250.9°C
• Density: 1.343g/cm³
• Vapor Pressure: 8.52E-10mmHg at 25°C
• Refractive Index: 1.696
• CAS DataBase Reference: 6-methyl-2-(2-nitrophenyl)-1H-benzimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-2-(2-nitrophenyl)-1H-benzimidazole(10173-72-5)
• EPA Substance Registry System: 6-methyl-2-(2-nitrophenyl)-1H-benzimidazole(10173-72-5)

Safety Data

• Hazardous Substances Data: 10173-72-5(Hazardous Substances Data)

Upstream product

• 496-72-0 4-methyl-1,2-diaminobenzene 
• 552-89-6 2-nitro-benzaldehyde 
• 578-46-1 5-methyl-2-nitroaniline 

Relevant articles and documents

Microwave-assisted one-pot synthesis of 2-(substituted phenyl)-1H- benzimidazole derivatives

A series of 2-(substituted phenyl)-1H-benzimidazole derivatives with various 5-and 6-position substituents (-H, -CH3, -CF3) were synthesized via microwave irradiation using a short synthetic route and Na2S2O5 as oxidant. This simple, fast, and efficient p

Solid Phase Synthesis of Biologically active Benzimidazole Derivatives Catalysed by CH3S03H-Si02 under Solvent free Condition

A simple an expeditious method was established for the synthesis of 2-Substituted-1H-Benzimidazole derivatives at 90°C using o-phenylenediamine and different aldehydes. It has been found that a mixture of Methanesulphonic acid-Si02to be an effective catal

Efficient method for the synthesis of benzimidazoquinazoline derivatives with three-point diversity

An efficient strategy for the preparation of a novel heterocyclic ring system of benzimidazoquinazolines with three-point diversity has been described. The compounds were obtained by treating o-phenylene diamines with o-nitrobenzaldehyde to give benzimidazoles, followed by reduction of the nitro group to give an amine. Derivatization of the resulting amine with isothiocyanates followed by in situ cyclodesulfurization at rt furnished the title compounds in high yields and purities. Copyright Taylor & Francis Group, LLC.