10174-83-1

Basic information

• Product Name: 2-BENZOYL-1-CYANO-6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE, 97
• Synonyms: 2-BENZOYL-1-CYANO-6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE, 97
• CAS NO: 10174-83-1
• Molecular Formula: C₁₉H₁₈N₂O₃
• Molecular Weight: 322.362
• Mol File: 10174-83-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 214-217°C
• Boiling Point: 460.98°C (rough estimate)
• Flash Point: 279.8°C
• Appearance: /
• Density: 1.2336 (rough estimate)
• Vapor Pressure: 1.1E-11mmHg at 25°C
• Refractive Index: 1.6140 (estimate)
• CAS DataBase Reference: 2-BENZOYL-1-CYANO-6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE, 97(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BENZOYL-1-CYANO-6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE, 97(10174-83-1)
• EPA Substance Registry System: 2-BENZOYL-1-CYANO-6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE, 97(10174-83-1)

Safety Data

• Hazardous Substances Data: 10174-83-1(Hazardous Substances Data)

Usage

Chemical Properties

white crystalline powder

InChI:InChI=1/C19H18N2O3/c1-23-17-10-14-8-9-21(19(22)13-6-4-3-5-7-13)16(12-20)15(14)11-18(17)24-2/h3-7,10-11,16H,8-9H2,1-2H3/t16-/m0/s1

Upstream product

• 1745-07-9 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 98-88-4 benzoyl chloride 
• 14174-17-5 (6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)(phenyl)methanone 
• 2179-92-2 tri-n-butyltin cyanide 
• 14301-36-1 N-[2-(3,4-dimethoxyphenyl)ethyl]formamide 
• 3382-18-1 6,7-dimethoxy-3,4-dihydro-isoquinoline 
• 151-50-8 potassium cyanide 
• 143-33-9 sodium cyanide 

Downstream Products

• 25186-59-8 1-benzo[1,3]dioxol-5-ylmethyl-2-benzoyl-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline-1-carbonitrile 
• 25186-62-3 1-benzo[1,3]dioxol-4-ylmethyl-2-benzoyl-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid methyl ester 
• 25186-61-2 1-benzo[1,3]dioxol-4-ylmethyl-2-benzoyl-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid 
• 863643-77-0 4-(2-benzoyl-1-cyano-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-1-ylmethyl)nicotinic acid ethyl ester 
• 25186-58-7 2-benzoyl-1-benzyl-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline-1-carbonitrile 
• 25186-60-1 1-benzo[1,3]dioxol-4-ylmethyl-2-benzoyl-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline-1-carbonitrile 

Relevant articles and documents

DDQ-promoted mild and efficient metal-free oxidative α-cyanation of N-acyl/sulfonyl 1,2,3,4-tetrahydroisoquinolines

A mild and highly efficient metal-free oxidative α-cyanation of N-acyl/sulfonyl 1,2,3,4-tetrahydroisoquinolines (THIQs) has been accomplished at an ambient temperature via DDQ oxidation and subsequent trapping of N-acyl/sulfonyl iminium ions with (n-Bu)s

IMPROVED SYNTHESIS OF DIHYDROISOQUINOLINE REISSERT COMPOUNDS

Conversion of a series of 3,4-dihydroisoquinolines to their corresponding Reissert compounds was improved significantly over the usual reaction conditions by buffering the reaction medium at pH 8.