101751-84-2

Upstream product

• 186581-53-3 diazomethane 
• 108-24-7 acetic anhydride 
• 28684-46-0 guibourtinidol-(4α<*>8)-catechin 
• 123131-42-0 (2R,3S,4S,2'R,3'S)-2'-(3,4-Dimethoxy-phenyl)-7,5',7'-trimethoxy-2-(4-methoxy-phenyl)-3,4,3',4'-tetrahydro-2H,2'H-[4,8']bichromenyl-3,3'-diol 

Relevant academic research and scientific papers

The structure and synthesis of proguibourtinidins from Cassia Abbreviata

An acetone extract of the bark of Cassia abbreviata yielded guibourtinidol-(4β → 8)-epiafzelechin, guibourtinidol-(4α → 8)-epiafzelechin, guibourtinidol-(4α → 8)-catechin, guibourtinidol-(4β →; 8)-epicatechin and ent-guibourtinidol-(4β → 8)-epicatechin. The structures of the proguibourtinidin dimers were confirmed by synthesis via mild acid-condensation. Guibourtinidol-(4α → 8)-afzelechin, previously isolated from Acacia leuderitzii, was also synthesized. Another two proguibourtinidol oligomers, namely, guibourtinidol-(4α → 8)-afzelechin and guibourtinidol(4α → 6)-afzelechin were products of the previous synthesis but neither of them have been reported to date. Copyright

Oligomeric Flavanoids. Part 1. Novel Dimeric Profisetinidins from Colophospermum mopane

The range of natural dimeric profisetidins is extended by the recognition of a series of novel (4,6)-coupled analogues based not only on (-)-fisetinidol but for the first time also on (+)-epifisetinidol as constituent units, e.g. the (-)-fisetinidol-(4α,6)- and (4β,6)-(+)-epifisetinidols.They are accompanied by bis(4α,6')-(-)-fisetinidol and (-)-fisetinidol-(4α,6')-(+)-epifisetinidol, the first prototypes of naturally ocurring B-ring coupled profisetinidins, and by the first dimeric peltogynoid analogue, (2S,3S,4R)-2,3-cis-3,4-trans-4mopanane-3',4',7-triol.

BIFLAVANOID PROGUIBOURTINIDIN CARBOXYLIC ACIDS AND THEIR BIFLAVANOID HOMOLOGUES FROM ACACIA LUEDERITZII

Key Word Index - Acacia luederitzii; Leguminosae; leucoguibourtinidins; proguibourtinidins; carboxylic acids; 3,4',7-trihydroxyflavanyls; regio-isomerism; diastereoisomers; 6-carboxyl-(+)-catechin; biflavanoids. - - and -proguibourtinidin carboxylic acids (3,7,4'-trihydroxyl functionality) of 2,3-trans-3,4-trans:2,3-cis- and 2,3-trans-3,4-trans:2,3-trans-configuration based on (-)-epicatechin or (+)-catechin as constituent units, and their associated biflavanoid homologues, predominate in the heartwood of Acacia luederitzii.They are accompanied by stereochemical and functional analogues and by their putative flavan-3,4-diol and flavan-3-ol precursors.