10176-63-3Relevant articles and documents
IMIDAZOPYRIDINES, COMPOSITIONS AND USE
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, (2008/06/13)
1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ones having an aryl or heteroaryl group in the 6-position, useful as phosphodiesterase inhibitors, are prepared by reacting a 2-amino-5-(aryl or heteroaryl)pyridine-3-carboxylic acid with diphenylphosphoryl azide. The compounds are of the formula where R1 and R3 are hydrogen or lower-alkyl, R5 is lower-alkyl or fluorinated lower-alkyl, and Ar is 4-or 3-pyridinyl, or N-oxides thereof, or phenyl or substituted phenyl.
Potential cardiotonic agents. Part 2: Synthesis and pharmacological properties of 5-(4-pyridinyl)- and 5-phenyl-substituted 3-cyano-6-methyl-2-oxaalkylamino-pyridines
Klauschenz,Rumler,Hagen,Hagen,Heer,Mitzner,Niedrich
, p. 23 - 25 (2007/10/02)
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