10177-23-8Relevant articles and documents
A pair of highly biotolerated diamagnetic and paramagnetic iron(II) complexes displaying electroneutrality
Wang,Gondrand,Touti,Hasserodt
, p. 15391 - 15395 (2015)
A pair of structurally analogous macrocyclic iron(ii) complexes with a magnetic off-on relationship is reported that exhibit electroneutrality at neutral pH and high stability in physiological media. This has been achieved by external charge compensation using nicotinate pendent arms. No contact toxicity was observed for cells up to 4 mM for the low-spin and 2 mM for the high-spin complex. These results are a necessary precursor to the future design of turn-on probes with elevated biotolerance.
Towards the synthesis of substituted porphyrins by a pyridyl group bearing a reactive functionality
Ojaimi, Maya El,Habermeyer, Benoit,Gros, Claude P.,Barbe, Jean-Michel
, p. 469 - 480 (2011/03/20)
Pyridyl-substituted porphyrins bearing a reactive functionality were prepared via Suzuki cross-coupling reactions and resulted in very good yields. These compounds are precursors of new porphyrin architectures able to coordinate two metals: one in the porphyrin core and the second around the pyridyl moiety. During the coupling reactions, a higher reactivity of a chloro picolyl group was evidenced compared to a bromo function on the same reacting molecule.
Syntheses and GABA uptake properties of 6-ether- and 6-enol ether-substituted nipecotic acids
N'Goka, Victor,Bissantz, Caterina,Bisel, Philippe,Stenbol, Tine B.,Krogsgaard-Larsen, Povl,Schlewer, Gilbert
, p. 633 - 638 (2007/10/03)
6-Aralkylether- and 6-arylenol-ether-substituted nipecotic acids were synthesized. These analogues are poor GABA uptake inhibitors. The electronegative region concept developed in the N-substituted nipecotic acid series cannot be transferred on the side c