1017781-46-2Relevant articles and documents
Intermediate compound for synthesizing nitrogen-containing heterocyclic ring and preparation method and application thereof
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, (2021/04/21)
The invention relates to an intermediate compound for synthesizing a nitrogen-containing heterocyclic ring and a preparation method and application thereof, and the chemical structural formula of the intermediate compound is as follows: amide, azodicarboxylate and carboxylic acid are used as raw materials, and under the action of a catalyst, the intermediate compound is prepared through direct carbon-hydrogen bond bifunctionalization synthesis. Compared with the prior art, the method has the advantages that the intermediate compound is synthesized through the direct carbon-hydrogen bond bifunctionalization process, the substrate can be expanded in a large range, different nitrogen-containing heterocycles can be obtained through different subsequent treatment, the structural diversity is achieved, and a new method is provided for industrial production of the nitrogen-containing heterocycles.
