101781-09-3

Basic information

• Product Name: Benzenepropanamine, N,N-dimethyl-a-(phenylmethyl)-
• Synonyms: Benzenepropanamine, N,N-dimethyl-a-(phenylmethyl)-
• CAS NO: 101781-09-3
• Molecular Formula: C18H23N
• Molecular Weight: 253.387
• Mol File: 101781-09-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenepropanamine, N,N-dimethyl-a-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanamine, N,N-dimethyl-a-(phenylmethyl)-(101781-09-3)
• EPA Substance Registry System: Benzenepropanamine, N,N-dimethyl-a-(phenylmethyl)-(101781-09-3)

Safety Data

• Hazardous Substances Data: 101781-09-3(Hazardous Substances Data)

Upstream product

• 5973-44-4 N,N-dimethyl-1,4-diphenylbut-3-yn-2-amine 
• 5830-31-9 N,N-dimethyl-3-phenylpropanamide 
• 3839-31-4 dimethyl(phenyl)silyllithium 
• 100106-80-7 Benzyl-dimethyl-<3-phenyl-propin-(2)-yl>-ammonium-Iodid 

Relevant articles and documents

Formation of α-dialkylamino alkyllithium intermediates in the reaction of N,N-dialkylamides with PhMe2SiLi followed by a second lithium reagent, and their alkylation, fragmentation, cyclisation and rearrangement by proton transfer

Tertiary amides (RCONMe2) react with PhMe2SiLi, followed by a second lithium reagent NuLi, to give α-dialkylamino alkyllithium intermediates R(Me2N)CLiNu that undergo protonation 2 → 3, alkylation 2a → 3ab, β-elimination 5 → 6, intramolecular attack on an isolated double bond 9 → 10, intramolecular proton transfer 12, 17 and 22 (arrows), and fragmentation 28 and 34 (arrows), depending upon the structures of the various components R and Nu.

STUDIES ON ACETYLENIC COMPOUNDS. XXXIV. REARRANGEMENT OF

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