Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1018069-81-2

TG 100801 (Hydrochloride) is a chemical agent that has been investigated for its potential use in medical applications. It is a potent and ATP competitive VEGF Receptor 2 inhibitor that also inhibits Flt-1 and Tie-2. TG 100801 (Hydrochloride) has been specifically engineered for its topical application to the eye, making it a promising candidate for ocular treatments.

1018069-81-2 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

  • Phenol, 4-chloro-3-[5-methyl-3-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-1,2,4-benzotriazin-7-yl]-, 1-benzoate, hydrochloride (1:1)

    Cas No: 1018069-81-2

  • USD $ 1.9-2.9 / Gram

  • 100 Gram

  • 1000 Metric Ton/Month

  • Chemlyte Solutions
  • Contact Supplier

  • Phenol, 4-chloro-3-[5-methyl-3-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-1,2,4-benzotriazin-7-yl]-, 1-benzoate, hydrochloride (1:1)

    Cas No: 1018069-81-2

  • No Data

  • No Data

  • No Data

  • Antimex Chemical Limied
  • Contact Supplier
  • 1018069-81-2 Structure

  • Basic information

    1. Product Name: TG 100801 (Hydrochloride)
    2. Synonyms: TG 100801 (Hydrochloride);TG 100801 HCl
    3. CAS NO:1018069-81-2
    4. Molecular Formula: C33H31Cl2N5O3
    5. Molecular Weight: 616.53694
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1018069-81-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: TG 100801 (Hydrochloride)(CAS DataBase Reference)
    10. NIST Chemistry Reference: TG 100801 (Hydrochloride)(1018069-81-2)
    11. EPA Substance Registry System: TG 100801 (Hydrochloride)(1018069-81-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1018069-81-2(Hazardous Substances Data)

1018069-81-2 Usage

Uses

Used in Ophthalmology:
TG 100801 (Hydrochloride) is used as a topical treatment for ocular inflammation and age-related macular degeneration. Its application in this field is due to its ability to inhibit VEGF Receptor 2, Flt-1, and Tie-2, which are key factors in the development of these conditions.
In the context of ocular inflammation, TG 100801 (Hydrochloride) is used as an anti-inflammatory agent to reduce inflammation and associated symptoms. Its inhibitory effects on VEGF Receptor 2 and other related factors help in controlling the inflammatory response in the eye.
For age-related macular degeneration, TG 100801 (Hydrochloride) is used as a therapeutic agent to slow down the progression of the disease. Its ability to inhibit VEGF Receptor 2 and related factors helps in reducing the formation of abnormal blood vessels and leakage in the retina, which are common features of age-related macular degeneration.

Check Digit Verification of cas no

The CAS Registry Mumber 1018069-81-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,1,8,0,6 and 9 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1018069-81:
(9*1)+(8*0)+(7*1)+(6*8)+(5*0)+(4*6)+(3*9)+(2*8)+(1*1)=132
132 % 10 = 2
So 1018069-81-2 is a valid CAS Registry Number.

1018069-81-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name [4-chloro-3-[5-methyl-3-[4-(2-pyrrolidin-1-ylethoxy)anilino]-1,2,4-benzotriazin-7-yl]phenyl] benzoate,hydrochloride

1.2 Other means of identification

Product number -
Other names Phenol,4-chloro-3-(5-methyl-3-((4-(2-(1-pyrrolidinyl)ethoxy)phenyl)amino)-1,2,4-benzotriazin-7-yl)-,1-benzoate,hydrochloride (1:1)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1018069-81-2 SDS

1018069-81-2Upstream product

1018069-81-2Downstream Products

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1018069-81-2