10183-64-9Relevant articles and documents
Total synthesis of (±)-decinine via an oxidative biaryl coupling with defined axial chirality
Shan, Zhen-Hua,Liu, Ji,Xu, Ling-Min,Tang, Ye-Feng,Chen, Jia-Hua,Yang, Zhen
, p. 3712 - 3715 (2012/09/21)
The total synthesis of (±)-decinine has been achieved. The key steps in the synthesis involved the formation of lasubine II via a gold catalyzed annulation of 1-(but-3-yn-1-yl)piperidine and the formation of the 12-membered ring of decinine (1) with complementary atropselectivity via a VOF 3-mediated oxidative biaryl coupling reaction.