101832-73-9

Basic information

• Product Name: 2,3-diMethyl-1H-Indol-7-aMine
• Synonyms: 2,3-diMethyl-1H-Indol-7-aMine
• CAS NO: 101832-73-9
• Molecular Formula: C₁₀H₁₂N₂
• Molecular Weight: 160.21568
• Mol File: 101832-73-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 366.9°Cat760mmHg
• Flash Point: 203.3°C
• Appearance: /
• Density: 1.172g/cm³
• Vapor Pressure: 1.42E-05mmHg at 25°C
• Refractive Index: 1.692
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 2,3-diMethyl-1H-Indol-7-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-diMethyl-1H-Indol-7-aMine(101832-73-9)
• EPA Substance Registry System: 2,3-diMethyl-1H-Indol-7-aMine(101832-73-9)

Safety Data

• Hazardous Substances Data: 101832-73-9(Hazardous Substances Data)

Usage

General Description

2,3-dimethyl-1H-indol-7-amine is a chemical compound with the molecular formula C11H12N2. It is an aromatic compound containing a indole ring with two methyl groups attached at the 2 and 3 position, and an amine group at the 7 position. This chemical is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs and bioactive compounds. It has also been studied for its potential pharmacological properties, including its potential use as an antitumor agent and its ability to inhibit the activity of certain enzymes. Additionally, 2,3-dimethyl-1H-indol-7-amine has been investigated for its potential role in the treatment of various neurological disorders and as a potential antiviral agent.

InChI:InChI=1/C10H12N2/c1-6-7(2)12-10-8(6)4-3-5-9(10)11/h3-5,12H,11H2,1-2H3

Upstream product

• 41018-86-4 2,3-dimethyl-7-nitro-1H-indole 
• 55899-45-1 2-methyl-indol-7-ylamine 

Relevant articles and documents

Hydrogen Bond Directed ortho-Selective C?H Borylation of Secondary Aromatic Amides

Reported is an iridium catalyst for ortho-selective C?H borylation of challenging secondary aromatic amide substrates, and the regioselectivity is controlled by hydrogen-bond interactions. The BAIPy-Ir catalyst forms three hydrogen bonds with the substrate during the crucial activation step, and allows ortho-C?H borylation with high selectivity. The catalyst displays unprecedented ortho selectivities for a wide variety of substrates that differ in electronic and steric properties, and the catalyst tolerates various functional groups. The regioselective C?H borylation catalyst is readily accessible and converts substrates on gram scale with high selectivity and conversion.

Isophthalamides and 2,6-dicarboxamidopyridines with pendant indole groups: A 'twisted' binding mode for selective fluoride recognition

Two cleft-like anion receptors have been synthesised that contain indole hydrogen-bond donors and show fluoride selectively in a DMSO-water solution with crystallographic studies showing a 'twisted' binding mode for fluoride in the solid state. The Royal Society of Chemistry.

Novel N-acylated heterocycles

Described are compositions comprising a muscarinic receptor antagonist and an N-acylated heterocycle derivative having affinity for serotonergic receptors, and enantiomers, diastereoisomers, N-oxides, polymorphs, solvates and pharmaceutically acceptable salts thereof. The combination of a muscarinic receptor antagonist and an N-acylated heterocycle, or an enantiomer, diastereoisomer, N-oxide, polymorph, solvate or pharmaceutically acceptable salt thereof, is useful in the treatment of patients with neuromuscular dysfunction of the lower urinary tract and diseases related to 5-HT1A receptors.