1018473-22-7

Basic information

• Product Name: 1-(6-chloropyrimidin-4-yl)-3-methyl-1H-pyrazol-5-amine
• Synonyms: 1-(6-chloropyrimidin-4-yl)-3-methyl-1H-pyrazol-5-amine;1H-Pyrazol-5-amine, 1-(6-chloro-4-pyrimidinyl)-3-methyl-
• CAS NO: 1018473-22-7
• Molecular Formula: C8H8ClN5
• Molecular Weight: 210
• Mol File: 1018473-22-7.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-(6-chloropyrimidin-4-yl)-3-methyl-1H-pyrazol-5-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(6-chloropyrimidin-4-yl)-3-methyl-1H-pyrazol-5-amine(1018473-22-7)
• EPA Substance Registry System: 1-(6-chloropyrimidin-4-yl)-3-methyl-1H-pyrazol-5-amine(1018473-22-7)

Safety Data

• Hazardous Substances Data: 1018473-22-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-(6-chloropyrimidin-4-yl)-3-methyl-1H-pyrazol-5-amine is used as a key intermediate in the synthesis of various pharmaceuticals for its potential to exhibit interesting biological activities. Its unique structure allows it to be a valuable component in the development of new drugs with specific therapeutic effects.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(6-chloropyrimidin-4-yl)-3-methyl-1H-pyrazol-5-amine is utilized as a building block in the creation of agrochemicals. Its reactivity and chemical properties make it suitable for the development of compounds that can be used in crop protection and other agricultural applications.
Used in Organic Chemistry:
1-(6-chloropyrimidin-4-yl)-3-methyl-1H-pyrazol-5-amine serves as an important intermediate in organic chemistry for the production of a wide range of chemical products. Its versatility in reactions and ability to form various derivatives contribute to its significance in the synthesis of complex organic molecules.

Upstream product

• 5767-35-1 6-chloro-4-hydrazinopyrimidine 
• 1118-60-1 3-iminobutyronitrile 

Downstream Products

• 1018471-71-0 3-(isopropylaminomethyl)-N-(4-methyl-3-(3-methyl-1-(6-methylaminopyrimidin-4-yl)-1H-pyrazol-5-ylamino)phenyl)-5-trifluoromethylbenzamide 
• 1018468-47-7 N-(5-(1-fluoro-1-methylethyl)pyridin-3-yl)-4-methyl-3-(5-methyl-2-(6-methylaminopyrimidin-4-yl)-2H-pyrazol-3-ylamino)benzamide 
• 1018473-30-7 tert-butl 4-methyl-3-(3-methyl-1-(6-methylaminopyrimidin-4-yl)-1H-pyrazol-5-ylamino)phenylcarbamate 
• 1018473-31-8 6-methyl-N₁-(3-methyl-1-(6-methylaminopyrimidin-4-yl)-1H-pyrazol-5-yl)benzen-1,3-diamine 

Relevant articles and documents

COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, ARG, BCR-Abl, BRK, EphB, Fms, Fyn, KDR, c-Kit, LCK, PDGF-R, b-Raf, c-Raf, SAPK2, Src, Tie2 and TrkB kinases.