10185-00-9 Usage
General Description
Delta(3)-chromene-3-carboxamide, also known as Lemborexant, is a chemical compound that acts as a potent dual orexin receptor antagonist. It is used for the treatment of insomnia, particularly in individuals who have difficulty falling asleep or staying asleep. Lemborexant works by blocking the binding of orexin, a neuropeptide that plays a role in regulating wakefulness and sleep-wake cycles, to its receptors in the brain. By doing so, it helps to promote sleep and improve overall sleep quality. This chemical has been approved for use in the United States and several other countries, and is available in tablet form for oral consumption. It is generally well-tolerated, with common side effects including headache, somnolence, and dizziness.
Check Digit Verification of cas no
The CAS Registry Mumber 10185-00-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,1,8 and 5 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 10185-00:
(7*1)+(6*0)+(5*1)+(4*8)+(3*5)+(2*0)+(1*0)=59
59 % 10 = 9
So 10185-00-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H9NO2/c11-10(12)8-5-7-3-1-2-4-9(7)13-6-8/h1-5H,6H2,(H2,11,12)
10185-00-9Relevant articles and documents
Chromene and Chroman 3-Carboxamides and Some Related Compounds as a New Class of Centrally Acting Agents
Gupta, R. C.,Pratap, Ram,Prasad, C. R.,Anand, Nitya
, p. 344 - 347 (2007/10/02)
A number of chromene-3-carboxamides (7), 3-Aminochromans (11) and 3-aminomethylchromans (9) have been synthesized.Chromene-3-carboxamides have been found to exhibit strong central muscle relaxant activity compared to mephesin.
