10186-66-0

Basic information

• Product Name: ETHYL 2-ETHOXY-2,3,3,3-TETRAFLUOROPROPANOATE
• Synonyms: ETHYL 2-ETHOXY-2,3,3,3-TETRAFLUOROPROPANOATE;ETHYL 2-ETHOXYTETRAFLUOROPROPIONATE;Ethyl2-ethoxy-2,3,3,3-tetrafluoropropionate
• CAS NO: 10186-66-0
• Molecular Formula: C₇H₁₀F₄O₃
• Molecular Weight: 218.15
• Mol File: 10186-66-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 204.9°Cat760mmHg
• Flash Point: 75.8°C
• Appearance: /
• Density: 1.24g/cm³
• Vapor Pressure: 0.258mmHg at 25°C
• Refractive Index: 1.357
• CAS DataBase Reference: ETHYL 2-ETHOXY-2,3,3,3-TETRAFLUOROPROPANOATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-ETHOXY-2,3,3,3-TETRAFLUOROPROPANOATE(10186-66-0)
• EPA Substance Registry System: ETHYL 2-ETHOXY-2,3,3,3-TETRAFLUOROPROPANOATE(10186-66-0)

Safety Data

• Hazardous Substances Data: 10186-66-0(Hazardous Substances Data)

Usage

General Description

ETHYL 2-ETHOXY-2,3,3,3-TETRAFLUOROPROPANOATE is a chemical compound with the molecular formula C6H9F4O3. It is a colorless liquid with a fruity odor and is commonly used as a solvent in various industrial and commercial applications. ETHYL 2-ETHOXY-2,3,3,3-TETRAFLUOROPROPANOATE is often utilized in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. It is also used as a reagent in organic synthesis and as a flavoring agent in food and beverage products. ETHYL 2-ETHOXY-2,3,3,3-TETRAFLUOROPROPANOATE is known for its low toxicity and relatively stable properties, making it a versatile and valuable chemical in various industries.

InChI:InChI=1/C7H10F4O3/c1-3-13-5(12)6(8,14-4-2)7(9,10)11/h3-4H2,1-2H3

Upstream product

• 64-17-5 ethanol 
• 10186-67-1 2-Aethoxy-tetrafluor-propionsaeure 
• 129880-37-1 Sodium; 2-ethoxy-2,3,3,3-tetrafluoro-propionate 
• 428-59-1 Hexafluoropropene oxide 
• 66-71-7 1,10-Phenanthroline 

Downstream Products

• 353-36-6 1-fluoroethane 
• 13081-18-0 ethyl-3,3,3-trifluoropyruvate 

Relevant articles and documents

Preparation method of 2-fluoro-2-alkyloxy trifluoropropionate

The invention discloses a preparation method of 2-fluoro-2-alkyloxy trifluoropropionate. In the presence of an organic alkali and/or an inorganic alkali, hexafluoropropylene oxide and alkyl alcohols carry out reactions to obtain corresponding 2-fluoro-2-alkyloxy trifluoropropionate. The provided method has the advantages of suitable reaction temperature, high reaction yield, good selectivity, little amount of waste solid, waste water, and waste gas, and easiness for industrialization. The prepared 2-fluoro-2-alkyloxy trifluoropropionate can be used as a trifluoromethylation reagent for the synthesis of novel medicines and pesticides.

Formylimine versus Isocyanate - an Unusual Tautomerism of a Trifluoroalanine Derivative

The intermediate 7a formed by hydrogen chloride elimination of 6 can easily tautomerize to the isolable isocyanate 7b.Depending on the reaction conditions nucleophiles react with 7a and 7b to give the corresponding products 8 or 9, respectively. Key Words