1018608-18-8Relevant articles and documents
Spirocyclic derivatives
-
Page/Page column 151, (2016/04/09)
The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease, disorder or condition ameliorated by inhibition of a dopamine transporter); and methods of treating patients with such compounds; wherein R1, R2, R3, R4, R5, R6, R9, R10, Q, X, Y, Z, A, L, B, m, n and p are as defined herein.
The discovery of new spirocyclic muscarinic M3 antagonists
Stocks, Michael J.,Alcaraz, Lilian,Bailey, Andrew,Bowers, Keith,Donald, David,Edwards, Helen,Hunt, Fraser,Kindon, Nicholas,Pairaudeau, Garry,Theaker, Jill,Warner, Daniel J.
scheme or table, p. 7458 - 7461 (2011/01/12)
The optimisation of a new series of high potency muscarinic M3 antagonists, derived from high throughput screening library hit is described.
