1018719-75-9

Basic information

• Product Name: ethyl 1-[(3,5-dibromophenyl)methyl]-3-[4-(1,1-dimethylethyl)phenyl]-1H-indole-2-carboxylate
• Synonyms: ethyl 1-[(3,5-dibromophenyl)methyl]-3-[4-(1,1-dimethylethyl)phenyl]-1H-indole-2-carboxylate
• CAS NO: 1018719-75-9
• Molecular Weight: 569.336
• Mol File: 1018719-75-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 1-[(3,5-dibromophenyl)methyl]-3-[4-(1,1-dimethylethyl)phenyl]-1H-indole-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-[(3,5-dibromophenyl)methyl]-3-[4-(1,1-dimethylethyl)phenyl]-1H-indole-2-carboxylate(1018719-75-9)
• EPA Substance Registry System: ethyl 1-[(3,5-dibromophenyl)methyl]-3-[4-(1,1-dimethylethyl)phenyl]-1H-indole-2-carboxylate(1018719-75-9)

Safety Data

• Hazardous Substances Data: 1018719-75-9(Hazardous Substances Data)

Upstream product

• 412006-68-9 ethyl 3-[4-(1,1-dimethylethyl)phenyl]-1H-indole-2-carboxylate 
• 56908-88-4 3,5-dibromobenzyl bromide 

Downstream Products

• 1010413-47-4 1-[(3,5-dibromophenyl)methyl]-3-[4-(1,1-dimethylethyl)phenyl]-1H-indole-2-carboxylic acid 

Relevant articles and documents

Process development and scale-up of a pparγ agonist: Selection of the manufacture route

Two short, high-yielding routes to the selective PPARγ agonist GSK376501A were developed and carried out on scale. The key bond -forming reaction in each synthesis was the substitution of a 3,5-difluoro or 3,5-dibromo aryl intermediate with 2-methoxy-etha