1018816-25-5

Basic information

• Product Name: ethyl 2-{4-[{[2-[2-(2,4-difluorophenyl)ethyl]-4-oxopyrido[2,3-d]pyrimidin-1(4H)-yl]acetyl}({4'-[(trifluoromethyl)oxy]-4-biphenylyl}-methyl)amino]-1-piperidinyl}-2-methylpropanoate
• Synonyms: ethyl 2-{4-[{[2-[2-(2,4-difluorophenyl)ethyl]-4-oxopyrido[2,3-d]pyrimidin-1(4H)-yl]acetyl}({4'-[(trifluoromethyl)oxy]-4-biphenylyl}-methyl)amino]-1-piperidinyl}-2-methylpropanoate
• CAS NO: 1018816-25-5
• Molecular Weight: 791.818
• Mol File: 1018816-25-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: ethyl 2-{4-[{[2-[2-(2,4-difluorophenyl)ethyl]-4-oxopyrido[2,3-d]pyrimidin-1(4H)-yl]acetyl}({4'-[(trifluoromethyl)oxy]-4-biphenylyl}-methyl)amino]-1-piperidinyl}-2-methylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-{4-[{[2-[2-(2,4-difluorophenyl)ethyl]-4-oxopyrido[2,3-d]pyrimidin-1(4H)-yl]acetyl}({4'-[(trifluoromethyl)oxy]-4-biphenylyl}-methyl)amino]-1-piperidinyl}-2-methylpropanoate(1018816-25-5)
• EPA Substance Registry System: ethyl 2-{4-[{[2-[2-(2,4-difluorophenyl)ethyl]-4-oxopyrido[2,3-d]pyrimidin-1(4H)-yl]acetyl}({4'-[(trifluoromethyl)oxy]-4-biphenylyl}-methyl)amino]-1-piperidinyl}-2-methylpropanoate(1018816-25-5)

Safety Data

• Hazardous Substances Data: 1018816-25-5(Hazardous Substances Data)

Upstream product

• 1018815-98-9 ethyl 2-methyl-2-(4-oxo-1-piperidinyl)propanoate 
• 600-00-0 ethyl 2-bromoisobutyrate 
• 41979-39-9 4-piperidone hydrochloride 
• 157788-40-4 4'-(trifluoromethoxy)-[1,1'-biphenyl]-4-carbonitrile 
• 1018816-07-3 ethyl [2-[2-(2,4-difluorophenyl)ethyl]-4-oxopyrido[2,3-d]pyrimidin-1(4H)-yl]acetate 
• 1018816-09-5 3-(2,4-difluorophenyl)-propanimidamide 
• 1018816-10-8 [2-[2-(2,4-difluorophenyl)ethyl]-4-oxopyrido[2,3-d]pyrimidin-1(4H)-yl]acetic acid 
• 1018816-03-9 ethyl 2-methyl-2-{4-[({4'-[(trifluoromethyl)oxy]-4-biphenylyl}methyl)amino]-1-piperidinyl}propanoate 

Relevant articles and documents

METHODS OF TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES AND DISORDERS

The present invention provides compositions and methods useful for treating and preventing neurodegenerative disease and neurologically related disorders by inhibition of Lp-PLA2. The compositions and methods are useful for treating and preventing disease

METHODS OF TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES AND DISORDERS

The present invention provides compostions and methods useful for treating and preventing neurodegenerative disease and neurologically related disorders by inhibition of Lp-PLA2. The compositions and methods are useful for treating and preventing diseases