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1018898-85-5

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1018898-85-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1018898-85-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,1,8,8,9 and 8 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1018898-85:
(9*1)+(8*0)+(7*1)+(6*8)+(5*8)+(4*9)+(3*8)+(2*8)+(1*5)=185
185 % 10 = 5
So 1018898-85-5 is a valid CAS Registry Number.

1018898-85-5Relevant articles and documents

Novel L-xylose derivatives as selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes

Goodwin, Nicole C.,Mabon, Ross,Harrison, Bryce A.,Shadoan, Melanie K.,Almstead, Zheng Y.,Xie, Yiling,Healy, Jason,Buhring, Lindsey M.,DaCosta, Christopher M.,Bardenhagen, Jennifer,Mseeh, Faika,Liu, Qingyun,Nouraldeen, Amr,Wilson, Alan G. E.,Kimball, S. David,Powell, David R.,Rawlins, David B.

supporting information; experimental part, p. 6201 - 6204 (2010/03/31)

The prevalence of diabetes throughout the world continues to increase and has become a major health issue. Recently there have been several reports of inhibitors directed toward the sodium-dependent glucose cotransporter 2 (SGLT2) as a method of maintaining glucose homeostasis in diabetic patients. Herein we report the discovery of the novel O-xyloside 7c that inhibits SGLT2 in vitro and urinary glucose reabsorption in vivo. 2009 American Chemical Society.

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