1018968-57-4Relevant articles and documents
Synthesis of the sporolide ring framework through a cascade sequence involving an intramolecular [4+2] cycloaddition reaction of an o-quinone
Nicolaou,Wang, Jianhua,Tang, Yefeng
, p. 1432 - 1435 (2008)
(Chemical Equation Presented) Sea-ing is believing: The o-quinone indene intermediate 1 was generated from the corresponding catechol substrate and converted into macrocycle 2 by a cascade sequence involving a novel intramolecular [4+2] cycloaddition reaction. This sequence serves as the key process to form the core heptacyclic structure 3 of the marine-derived natural products sporolide A and B, which were isolated from the relevant actinomycete fermentation broths.