1019-03-0 Usage
Uses
Used in Pharmaceutical Industry:
2-Propylquinoline-4-carboxylic acid is used as a potential therapeutic agent for various conditions due to its demonstrated anti-inflammatory and antitumor properties. Its ability to modulate inflammatory responses and inhibit tumor growth makes it a candidate for the treatment of inflammatory diseases and cancer.
Used in Neurodegenerative Disease Treatment:
In the field of neurodegenerative diseases, 2-propylquinoline-4-carboxylic acid is used as a potential treatment for Alzheimer's disease, given its capacity to inhibit the formation of beta-amyloid fibrils, which are a hallmark of the condition.
Used in Medicinal Chemistry Research:
2-Propylquinoline-4-carboxylic acid is utilized as a subject of research for further development in medicinal chemistry, where its structure and properties are being investigated to discover new applications and enhance its therapeutic potential for a range of diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1019-03-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,1 and 9 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1019-03:
(6*1)+(5*0)+(4*1)+(3*9)+(2*0)+(1*3)=40
40 % 10 = 0
So 1019-03-0 is a valid CAS Registry Number.
InChI:InChI=1/C13H13NO2/c1-2-5-9-8-11(13(15)16)10-6-3-4-7-12(10)14-9/h3-4,6-8H,2,5H2,1H3,(H,15,16)
1019-03-0Relevant articles and documents
Microwave Assisted Synthesis and Antimicrobial Potential of Quinoline-Based 4-Hydrazide-Hydrazone Derivatives
Ajani, Olayinka O.,Iyaye, King T.,Audu, Oluwatosin Y.,Olorunshola, Shade J.,Kuye, Alice O.,Olanrewaju, Ifedolapo O.
supporting information, p. 302 - 312 (2017/11/23)
Quinoline is a benzo-fused pyridine which is a therapeutically important heterocycle in medicinal chemistry research and new drug development. A series of 12 new hydrazide-hydrazone motifs bearing quinoline core 4a–l was successfully synthesized by microwave irradiation technique. The synthesis involved four steps strategies which was initiated by ring-opening synthetic modification of isatin to quinoline-4-carboxylic acid through Pfitzinger approach. The structure of the reactive intermediates 1, 2, and 3 as well as the targeted quinoline 4a–l were confirmed by the result of physicochemical parameters and spectroscopic means which include FTIR, UV, 1H and 13C NMR as well as DEPT 135 NMR. The in vitro antimicrobial screening of the targeted hydrazide-hydrazones 4a–l alongside with gentamicin (clinical standard) against six microorganisms was determined using agar diffusion. The result from the MIC test showed that this series of hydrazide-hydrazones exhibited remarkable efficacy as antimicrobial agents with 4e being the most active antibacterial agent with MIC value ranging from 3.13 to 0.39?μg/mL on the six organisms tested.
