10190-99-5

Basic information

• Product Name: ARISTOLOCHIC ACID SODIUM SALT
• Synonyms: 4-d)-1,3-dioxole-5-carboxylicacid,8-methoxy-6-nitro-phenanthro(sodiumsal;8-methoxy-6-nitrophenanthro(3,4-d)-1,3-dioxole-5-carboxylicacidsodiumsalt;sodiumaristolochatei;ARISTOLOCHIC ACID SODIUM SALT;aristolochic acid sodium;sodium 8-methoxy-6-nitrophenanthro[3,4-d]-1,3-dioxole-5-carboxylate;6-Nitro-8-methoxyphenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid sodium salt;8-Methoxy-3,4-methylenedioxy-10-nitrophenanthrene-1-carboxylic acid sodium salt
• CAS NO: 10190-99-5
• Molecular Formula: C17H10NNaO7
• Molecular Weight: 363.25
• EINECS: 233-463-4
• Mol File: 10190-99-5.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 615.5 °C at 760 mmHg
• Flash Point: 326 °C
• Appearance: orange/powder
• Density: g/cm³
• Vapor Pressure: 5.24E-16mmHg at 25°C
• Storage Temp.: 2-8°C
• Solubility: H2O: 50 mg/mL
• CAS DataBase Reference: ARISTOLOCHIC ACID SODIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: ARISTOLOCHIC ACID SODIUM SALT(10190-99-5)
• EPA Substance Registry System: ARISTOLOCHIC ACID SODIUM SALT(10190-99-5)

Safety Data

• Hazard Codes: T
• Statements: 23/24/25-40
• Safety Statements: 22-36/37/39-45
• RIDADR: 2811
• WGK Germany: 3
• RTECS: SF8281000
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 10190-99-5(Hazardous Substances Data)

Usage

Hazard

Suspected carcinogen.

Biochem/physiol Actions

Component of some Chinese herbal medicines, and responsible for their nephrotoxicity. Prodrug activated by reduction of the nitro group to an amine, which forms cytotoxic DNA adducts.

Safety Profile

Suspected carcinogen. Mutation data reported. When heated to decomposition it emits toxic vapors of NOx.

InChI:InChI=1/C17H11NO7.Na/c1-23-12-4-2-3-8-9(12)5-11(18(21)22)14-10(17(19)20)6-13-16(15(8)14)25-7-24-13;/h2-6H,7H2,1H3,(H,19,20);/q;+1/p-1